Bovine leukemia virus tax gene/Tax protein polymorphism and its relation to Enzootic Bovine Leukosis

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Bovine leukaemia virus and enzootic bovine leukosis.

Infection of bovines with bovine leukaemia virus (BLV) manifests itself in either of two ways: 30-70% of carriers develop persistent lymphocytosis (PL), with the viral genome integrated at a large number of different sites in the DNA of the affected B-lymphocytes, without causing any chromosomal abnormalities. Only 0,1-10% of carriers develop lymphoid tumours, which also consist of B-lymphocyte...

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Enzootic Bovine Leukosis

Bovine Leukemia Virus (BLV) is the etiologic agent of Enzootic Bovine Leukosis, a retrovirus exogenous to the bovine species. Once infected, there is no detectable viraemia but instead there is a strong and persistent immunological response to BLV structural proteins, essentially the gp51 envelope glycoprotein and the mayor core protein p24. We describe the test procedure of an indirect ELISA (...

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Enzootic Bovine Leukosis

Both EBL and SBL occur in southern Africa and in the Southern African context it will therefore be very important to accurately differentiate between EBL and SBL. The epidemiology, direct and indirect economic impact, diagnosis and most importantly control and eradication of EBL is markedly different to that of SBL. Globally EBL infection may also place severe restrictions on the import and exp...

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Detection and Identification of Enzootic Bovine Leukosis (EBL) in Calves in Iran

Enzootic bovine leukosis (EBL) is known as bovine lymphosarcoma and normally affects the old cattle. EBL is caused by bovine leukemia virus (BLV), which is generally spread all around the world. This virus is transmitted via bovine blood products within and between cattle herds. Glycoprotein GP51 in the blood is responsible for cattle immune responses to BLV. This virus has been previously dete...

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Bovine Leukaemia Virus onco-protein Tax antigen identification in human lymphomas tissue

Background: Bovine leukaemia virus (BLV) is the primary cause of enzootic bovine leukaemia which belongs to the HTLV/BLV group of oncogenic retroviruses including Human T-cell leukaemia virus types 1, 2, and 3 and simian T-lymphotropic virus. Due to daily consumption of milk, meat and other dairy by-products, a possible role in appearing human cancers can be assumed for BLV. Materials and Metho...

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ژورنال

عنوان ژورنال: Virulence

سال: 2019

ISSN: 2150-5594,2150-5608

DOI: 10.1080/21505594.2019.1708051